Indian Journal of Pathology and Microbiology (Jan 2012)
A 60-year-old lady with leonine facies: A rare diagnosis
Abstract
Systemic mastocytosis is a rare clonal disorder characterized by mast cell infiltration of one or more organs, with or without skin involvement. Leonine facies is a rare presentation and corresponds to the morphologic manifestation of diffuse dermal infiltration of the face as a result of long standing disease. Bone marrow aspiration and biopsy findings in a 60-year-old woman, who had extensive cutaneous infiltration due to systemic mastocytosis, resulting in ′leonine facies,′ are described, and causes of leonine facies are discussed.
Keywords