Asian Journal of Pharmaceutical Sciences (May 2021)

Drug-drug cocrystals: Opportunities and challenges

  • Xiaojuan Wang,
  • Shuzhang Du,
  • Rui Zhang,
  • Xuedong Jia,
  • Ting Yang,
  • Xiaojian Zhang

Journal volume & issue
Vol. 16, no. 3
pp. 307 – 317

Abstract

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Recently, drug-drug cocrystal attracts more and more attention. It offers a low risk, low-cost but high reward route to new and better medicines and could improve the physiochemical and biopharmaceutical properties of a medicine by addition of a suitable therapeutically effective component without any chemical modification. Having so many advantages, to date, the reported drug-drug cocrystals are rare. Here we review the drug-drug cocrystals that reported in last decade and shed light on the opportunities and challenges for the development of drug-drug cocrystals.

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