Dermatopathology (Nov 2017)

A 71-Year-Old Female with Myocardial Infarction and Long-Standing Ulcers on the Thigh

  • Eduardo De Flammineis,
  • Patrick M. Mulvaney,
  • Stefan Kraft,
  • Martin C. Mihm Jr.,
  • Shinjita Das,
  • Daniela Kroshinsky

DOI
https://doi.org/10.1159/000481727
Journal volume & issue
Vol. 4, no. 1-4
pp. 18 – 23

Abstract

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Calciphylaxis is most commonly encountered in patients with end-stage renal disease; however, it is increasingly observed in nonuremic patients as well. It is important to consider and diagnose nonuremic calciphylaxis early, as prompt treatment and mitigation of associated risk factors is essential to improve long-term outcomes for these patients. Here, we present the case of a 71-year-old woman with atrial fibrillation on warfarin, but without renal disease, who presented with two long-standing ulcers on her thigh and was diagnosed with the aid of biopsy with calciphylaxis. We review the existing literature on the subject and offer this case as a representative report of a clinicopathologic correlation for this disorder.

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