Emerging Infectious Diseases (Oct 2009)

Diversity and Origin of Dengue Virus Serotypes 1, 2, and 3, Bhutan

  • Tandin Dorji,
  • In-Kyu Yoon,
  • Edward C. Holmes,
  • Sonam Wangchuk,
  • Tashi Tobgay,
  • Ananda Nisalak,
  • Piyawan Chinnawirotpisan,
  • Kanittha Sangkachantaranon,
  • Robert V. Gibbons,
  • Richard G. Jarman

DOI
https://doi.org/10.3201/eid1510.090123
Journal volume & issue
Vol. 15, no. 10
pp. 1630 – 1632

Abstract

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To determine the serotype and genotype of dengue virus (DENV) in Bhutan, we conducted phylogenetic analyses of complete envelope gene sequences. DENV-2 (Cosmopolitan genotype) predominated in 2004, and DENV-3 (genotype III) predominated in 2005–2006; these viruses were imported from India. Primary dengue infections outnumbered secondary infections, suggesting recent emergence.

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