Comparative study of frontal QRS-T angle and inflammatory parameters in obsessive compulsive disorder patients and healthy control group

Abstract

It is argued that the average life expectancy for obsessive-compulsive disorder (OCD) decreases. However, data on the reasons for this are limited. This study compared sociodemographic characteristics, electrocardiogram (ECG) parameters, and laboratory values of 56 patients diagnosed with OCD with 60 healthy controls. We aimed to interpret the risk of cardiovascular disease in OCD through ECG parameters. OCD patients and the control group did not differ statistically in age or gender (p=0.689 and p=0.756, accordingly). Patient's with OCD have significantly longer corrected QT interval (QTc) (p=0.001). In comparison to the control group, OCD patients had statistically greater frontal QRS-T angle (fQRS-T) (p=0.044). The levels of platelet-to-lymphocyte ratio (PLR), pan immune inflammation value (PIV), and systemic immune inflammation index (SII) were elevated significantly in OCD patients (p=0.001, p=0.002, and p=0.009, respectively). The monocytes to high-density lipoprotein cholesterol (HDL-C) ratio (MHR) and atherogenic index of plasma (AIP) values of OCD patients were significantly greater than those of the control group (p [Med-Science 2022; 11(4.000): 1473-7]

Keywords

• obsessive-compulsive disorder
• frontal qrs-t angle
• monosit hdl ratio
• atherogenic index of plasma