Recent advances in coaxial electrospun nanofibers for wound healing

Jing Zhao; Liyun Chen; Aiwei Ma; Xujue Bai; Yating Zeng; Daojun Liu; Bo Liu; Wancong Zhang; Shijie Tang

Materials Today Bio (Dec 2024)

Recent advances in coaxial electrospun nanofibers for wound healing

Jing Zhao,
Liyun Chen,
Aiwei Ma,
Xujue Bai,
Yating Zeng,
Daojun Liu,
Bo Liu,
Wancong Zhang,
Shijie Tang

Affiliations

Jing Zhao: Department of Plastic Surgery and Burn Center, Second Affiliated Hospital, Shantou University Medical College, Shantou, Guangdong, 515041, China; Plastic Surgery Institute of Shantou University Medical College, Shantou Plastic Surgery Clinical Research Center, Shantou, Guangdong, 515041, China
Liyun Chen: Department of Plastic Surgery and Burn Center, Second Affiliated Hospital, Shantou University Medical College, Shantou, Guangdong, 515041, China; Plastic Surgery Institute of Shantou University Medical College, Shantou Plastic Surgery Clinical Research Center, Shantou, Guangdong, 515041, China
Aiwei Ma: Department of Plastic Surgery and Burn Center, Second Affiliated Hospital, Shantou University Medical College, Shantou, Guangdong, 515041, China; Plastic Surgery Institute of Shantou University Medical College, Shantou Plastic Surgery Clinical Research Center, Shantou, Guangdong, 515041, China
Xujue Bai: Department of Plastic Surgery and Burn Center, Second Affiliated Hospital, Shantou University Medical College, Shantou, Guangdong, 515041, China; Plastic Surgery Institute of Shantou University Medical College, Shantou Plastic Surgery Clinical Research Center, Shantou, Guangdong, 515041, China
Yating Zeng: Department of Plastic Surgery and Burn Center, Second Affiliated Hospital, Shantou University Medical College, Shantou, Guangdong, 515041, China; Plastic Surgery Institute of Shantou University Medical College, Shantou Plastic Surgery Clinical Research Center, Shantou, Guangdong, 515041, China
Daojun Liu: Department of Pharmacy, Shantou University Medical College, Shantou, 515041, China
Bo Liu: Chemistry and Chemical Engineering Guangdong Laboratory, Shantou, 515031, China; Corresponding author. Chemistry and Chemical Engineering Guangdong Laboratory, Shantou, 515031, China.
Wancong Zhang: Department of Plastic Surgery and Burn Center, Second Affiliated Hospital, Shantou University Medical College, Shantou, Guangdong, 515041, China; Plastic Surgery Institute of Shantou University Medical College, Shantou Plastic Surgery Clinical Research Center, Shantou, Guangdong, 515041, China; Corresponding author. Plastic Surgery Institute of Shantou University Medical College, Shantou Plastic Surgery Clinical Research Center, Shantou, Guangdong, 515041, China.
Shijie Tang: Department of Plastic Surgery and Burn Center, Second Affiliated Hospital, Shantou University Medical College, Shantou, Guangdong, 515041, China; Plastic Surgery Institute of Shantou University Medical College, Shantou Plastic Surgery Clinical Research Center, Shantou, Guangdong, 515041, China; Corresponding author. Department of Plastic Surgery and Burn Center, Second Affiliated Hospital, Shantou University Medical College, Shantou, Guangdong, 515041, China.

Journal volume & issue: Vol. 29
p. 101309

Abstract

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The skin is the body's primary immune barrier, defending it against pathogenic invasion. Skin injuries impose a significant physiological burden on patients, making effective wound management essential. Dressings are commonly employed in wound care, and electrospun nanofiber dressings are a research hotspot owing to their ease of fabrication, cost-effectiveness, and structural similarity to the extracellular matrix. Coaxial electrospinning offers considerable advantages in drug delivery, fiber structure transformation, and enhanced interaction with the host. These attributes make coaxial electrospun materials promising candidates for precision and personalized wound dressings in medical treatments. This review provides a comprehensive overview of wound healing and its influencing factors. It also outlines coaxial electrospinning's production principles and benefits in wound dressings. Guided by the factors affecting wound healing, coaxial electrospun nanofiber dressings have different application modalities. Furthermore, we discuss the current limitations and future directions for enhancing the current coaxial electrospun dressing technologies.

Published in Materials Today Bio

ISSN: 2590-0064 (Online)
Publisher: Elsevier
Country of publisher: Netherlands
LCC subjects: Medicine: Medicine (General); Science: Biology (General)
Website: https://www.journals.elsevier.com/materials-today-bio

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