Nature Communications (Feb 2022)
Kastor and Polluks polypeptides encoded by a single gene locus cooperatively regulate VDAC and spermatogenesis
- Shintaro Mise,
- Akinobu Matsumoto,
- Keisuke Shimada,
- Toshiaki Hosaka,
- Masatomo Takahashi,
- Kazuya Ichihara,
- Hideyuki Shimizu,
- Chisa Shiraishi,
- Daisuke Saito,
- Mikita Suyama,
- Tomoharu Yasuda,
- Toru Ide,
- Yoshihiro Izumi,
- Takeshi Bamba,
- Tomomi Kimura-Someya,
- Mikako Shirouzu,
- Haruhiko Miyata,
- Masahito Ikawa,
- Keiichi I. Nakayama
Affiliations
- Shintaro Mise
- Division of Cell Biology, Medical Institute of Bioregulation, Kyushu University, Fukuoka
- Akinobu Matsumoto
- Division of Cell Biology, Medical Institute of Bioregulation, Kyushu University, Fukuoka
- Keisuke Shimada
- Department of Experimental Genome Research, Research Institute for Microbial Diseases, Osaka University
- Toshiaki Hosaka
- Laboratory for Protein Functional and Structural Biology, RIKEN Center for Biosystems Dynamics Research
- Masatomo Takahashi
- Division of Metabolomics, Medical Institute of Bioregulation, Kyushu University, Fukuoka
- Kazuya Ichihara
- Division of Cell Biology, Medical Institute of Bioregulation, Kyushu University, Fukuoka
- Hideyuki Shimizu
- Division of Cell Biology, Medical Institute of Bioregulation, Kyushu University, Fukuoka
- Chisa Shiraishi
- Division of Cell Biology, Medical Institute of Bioregulation, Kyushu University, Fukuoka
- Daisuke Saito
- Division of Bioinformatics, Medical Institute of Bioregulation, Kyushu University, Fukuoka
- Mikita Suyama
- Division of Bioinformatics, Medical Institute of Bioregulation, Kyushu University, Fukuoka
- Tomoharu Yasuda
- Department of Immunology, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima
- Toru Ide
- Graduate School of Interdisciplinary Science and Engineering in Health Systems, Okayama University, Okayama
- Yoshihiro Izumi
- Division of Metabolomics, Medical Institute of Bioregulation, Kyushu University, Fukuoka
- Takeshi Bamba
- Division of Metabolomics, Medical Institute of Bioregulation, Kyushu University, Fukuoka
- Tomomi Kimura-Someya
- Laboratory for Protein Functional and Structural Biology, RIKEN Center for Biosystems Dynamics Research
- Mikako Shirouzu
- Laboratory for Protein Functional and Structural Biology, RIKEN Center for Biosystems Dynamics Research
- Haruhiko Miyata
- Department of Experimental Genome Research, Research Institute for Microbial Diseases, Osaka University
- Masahito Ikawa
- Department of Experimental Genome Research, Research Institute for Microbial Diseases, Osaka University
- Keiichi I. Nakayama
- Division of Cell Biology, Medical Institute of Bioregulation, Kyushu University, Fukuoka
- DOI
- https://doi.org/10.1038/s41467-022-28677-y
- Journal volume & issue
-
Vol. 13,
no. 1
pp. 1 – 17
Abstract
A number of testes-specific lncRNAs have been annotated but their roles remain largely unexplored. Here the authors identify two small peptides encoded by the lncRNA Gm9999, Kastor and Polluks, both of which are required for male fertility in mice.
