IJU Case Reports (Jan 2023)

A rare case of a clear cell carcinoma in a female urethral diverticulum

  • Masakazu Gonda,
  • Toshiki Etani,
  • Masahiko Isogai,
  • Kengo Kawase,
  • Takashi Nagai,
  • Teruaki Sugino,
  • Taku Naiki,
  • Shuzo Hamamoto,
  • Noriyasu Kawai,
  • Takahiro Yasui

DOI
https://doi.org/10.1002/iju5.12544
Journal volume & issue
Vol. 6, no. 1
pp. 77 – 80

Abstract

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Introduction Urethral clear cell carcinoma is rare and often arises from a urethral diverticulum and rarely from the Müllerian duct. However, an explanation for this correlation remains unknown. Case presentation We report the case of a 46‐year‐old woman who presented with hypermenorrhea. Magnetic resonance imaging revealed a papillary tumor in a cystic lesion in the dorsal urethra. We performed a robot‐assisted radical cystourethrectomy and created an ileal conduit. Since pathological findings revealed microvascular and lymphovascular invasions around the urethra, adjuvant radiation therapy was administered. The patient showed no signs of recurrence or metastasis after treatment. Conclusion We report a case of clear cell carcinoma in a female urethral diverticulum originating from a Müllerian duct cyst. While postoperative radiation therapy has been shown to produce a good outcome in carcinoma cases similar to this one, we recommend that a radical cystourethrectomy be performed.

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