Emerging Infectious Diseases (Apr 2014)

Diagnostic Methods for and Clinical Pictures of Polyomavirus Primary Infections in Children, Finland

  • Tingting Chen,
  • Laura Tanner,
  • Ville Simell,
  • Lea Hedman,
  • Marjaana Mäkinen,
  • Mohammadreza Sadeghi,
  • Riitta Veijola,
  • Heikki Hyöty,
  • Jorma Ilonen,
  • Mikael Knip,
  • Jorma Toppari,
  • Olli Simell,
  • Maria Söderlund-Venermo,
  • Klaus Hedman

DOI
https://doi.org/10.3201/eid2004.131015
Journal volume & issue
Vol. 20, no. 4
pp. 689 – 692

Abstract

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We used comprehensive serodiagnostic methods (IgM, IgG, and IgG avidity) and PCR to study Merkel cell polyomavirus and trichodysplasia spinulosa-associated polyomavirus infections in children observed from infancy to adolescence. Comparing seroconversion intervals with previous and subsequent intervals, we found that primary infections with these 2 viruses were asymptomatic in childhood.

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