An osmium-peroxo complex for photoactive therapy of hypoxic tumors

Nong Lu; Zhihong Deng; Jing Gao; Chao Liang; Haiping Xia; Pingyu Zhang

doi:10.1038/s41467-022-29969-z

Nature Communications (Apr 2022)

An osmium-peroxo complex for photoactive therapy of hypoxic tumors

Nong Lu,
Zhihong Deng,
Jing Gao,
Chao Liang,
Haiping Xia,
Pingyu Zhang

Affiliations

Nong Lu: College of Chemistry and Environmental Engineering, Shenzhen University
Zhihong Deng: Shenzhen Grubbs Institute, Department of Chemistry, Southern University of Science and Technology
Jing Gao: Shenzhen Grubbs Institute, Department of Chemistry, Southern University of Science and Technology
Chao Liang: College of Chemistry and Environmental Engineering, Shenzhen University
Haiping Xia: Shenzhen Grubbs Institute, Department of Chemistry, Southern University of Science and Technology
Pingyu Zhang: College of Chemistry and Environmental Engineering, Shenzhen University

DOI: https://doi.org/10.1038/s41467-022-29969-z
Journal volume & issue: Vol. 13, no. 1
pp. 1 – 11

Abstract

Read online

Photodynamic therapy has been a promising technique for the treatment of tumours. In this manuscript, the authors report on the photoactivation of the osmium peroxo complex and its potential use for chemotherapy and photodynamic therapy under blue light irradiation against tumours in their hypoxic environment.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

About the journal