SAPHO syndrome with a purely osteolytic form: A case report

Akira Kakiuchi, MD; Yayoi Yamamoto, MD, PhD; Akira Kanbe, MD; Daichi Kojima, MD; Ayako Hino, MD, PhD; Ayumi Horikawa, MD, PhD; Tsunehiro Doiuchi, MD; Hiroaki Kurihara, MD, PhD

Radiology Case Reports (Oct 2023)

SAPHO syndrome with a purely osteolytic form: A case report

Akira Kakiuchi, MD,
Yayoi Yamamoto, MD, PhD,
Akira Kanbe, MD,
Daichi Kojima, MD,
Ayako Hino, MD, PhD,
Ayumi Horikawa, MD, PhD,
Tsunehiro Doiuchi, MD,
Hiroaki Kurihara, MD, PhD

Affiliations

Akira Kakiuchi, MD: Corresponding author.; Department of Diagnostic and Interventional Radiology, Kanagawa Cancer Center, 2-3-2 Nakao Asahi-ku, Yokohama, Kanagawa, Japan
Yayoi Yamamoto, MD, PhD: Department of Diagnostic and Interventional Radiology, Kanagawa Cancer Center, 2-3-2 Nakao Asahi-ku, Yokohama, Kanagawa, Japan
Akira Kanbe, MD: Department of Diagnostic and Interventional Radiology, Kanagawa Cancer Center, 2-3-2 Nakao Asahi-ku, Yokohama, Kanagawa, Japan
Daichi Kojima, MD: Department of Diagnostic and Interventional Radiology, Kanagawa Cancer Center, 2-3-2 Nakao Asahi-ku, Yokohama, Kanagawa, Japan
Ayako Hino, MD, PhD: Department of Diagnostic and Interventional Radiology, Kanagawa Cancer Center, 2-3-2 Nakao Asahi-ku, Yokohama, Kanagawa, Japan
Ayumi Horikawa, MD, PhD: Department of Diagnostic and Interventional Radiology, Kanagawa Cancer Center, 2-3-2 Nakao Asahi-ku, Yokohama, Kanagawa, Japan
Tsunehiro Doiuchi, MD: Department of Diagnostic and Interventional Radiology, Kanagawa Cancer Center, 2-3-2 Nakao Asahi-ku, Yokohama, Kanagawa, Japan
Hiroaki Kurihara, MD, PhD: Department of Diagnostic and Interventional Radiology, Kanagawa Cancer Center, 2-3-2 Nakao Asahi-ku, Yokohama, Kanagawa, Japan

Journal volume & issue: Vol. 18, no. 10
pp. 3612 – 3614

Abstract

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SAPHO (synovitis, acne, pustulosis, hyperostosis, and osteitis) syndrome is a rare, chronic autoinflammatory disorder that can present with a constellation of cutaneous and osteoarticular symptoms. Osteodestructive lesions are not pathognomonic, whereas hyperostosis and osteitis are the most prominent imaging findings. We report the case of a man with osteolytic changes of the lumbar vertebra and a history of palmoplantar pustulosis. Biopsy revealed no neoplasm, suggesting SAPHO syndrome. Our case demonstrates that knowledge of atypical radiologic findings is necessary for the diagnosis of SAPHO syndrome.

Published in Radiology Case Reports

ISSN: 1930-0433 (Online)
Publisher: Elsevier
Country of publisher: United States
LCC subjects: Medicine: Medicine (General): Medical physics. Medical radiology. Nuclear medicine
Website: https://www.sciencedirect.com/journal/radiology-case-reports

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