Nature Communications (Jun 2020)
Proline-rich protein PRR19 functions with cyclin-like CNTD1 to promote meiotic crossing over in mouse
- Anastasiia Bondarieva,
- Kavya Raveendran,
- Vladyslav Telychko,
- H. B. D. Prasada Rao,
- Ramya Ravindranathan,
- Chrysoula Zorzompokou,
- Friederike Finsterbusch,
- Ihsan Dereli,
- Frantzeskos Papanikos,
- Daniel Tränkner,
- Alexander Schleiffer,
- Ji-Feng Fei,
- Anna Klimova,
- Masaru Ito,
- Dhananjaya S. Kulkarni,
- Ingo Roeder,
- Neil Hunter,
- Attila Tóth
Affiliations
- Anastasiia Bondarieva
- Institute of Physiological Chemistry, Faculty of Medicine Carl Gustav Carus, Technische Universität Dresden
- Kavya Raveendran
- Institute of Physiological Chemistry, Faculty of Medicine Carl Gustav Carus, Technische Universität Dresden
- Vladyslav Telychko
- Institute of Physiological Chemistry, Faculty of Medicine Carl Gustav Carus, Technische Universität Dresden
- H. B. D. Prasada Rao
- Howard Hughes Medical Institute, University of California Davis
- Ramya Ravindranathan
- Institute of Physiological Chemistry, Faculty of Medicine Carl Gustav Carus, Technische Universität Dresden
- Chrysoula Zorzompokou
- Institute of Physiological Chemistry, Faculty of Medicine Carl Gustav Carus, Technische Universität Dresden
- Friederike Finsterbusch
- Institute of Physiological Chemistry, Faculty of Medicine Carl Gustav Carus, Technische Universität Dresden
- Ihsan Dereli
- Institute of Physiological Chemistry, Faculty of Medicine Carl Gustav Carus, Technische Universität Dresden
- Frantzeskos Papanikos
- Institute of Physiological Chemistry, Faculty of Medicine Carl Gustav Carus, Technische Universität Dresden
- Daniel Tränkner
- Institute of Physiological Chemistry, Faculty of Medicine Carl Gustav Carus, Technische Universität Dresden
- Alexander Schleiffer
- Research Institute of Molecular Pathology (IMP)
- Ji-Feng Fei
- Institute for Brain Research and Rehabilitation, South China Normal University
- Anna Klimova
- National Center for Tumor Diseases (NCT)
- Masaru Ito
- Howard Hughes Medical Institute, University of California Davis
- Dhananjaya S. Kulkarni
- Howard Hughes Medical Institute, University of California Davis
- Ingo Roeder
- National Center for Tumor Diseases (NCT)
- Neil Hunter
- Howard Hughes Medical Institute, University of California Davis
- Attila Tóth
- Institute of Physiological Chemistry, Faculty of Medicine Carl Gustav Carus, Technische Universität Dresden
- DOI
- https://doi.org/10.1038/s41467-020-16885-3
- Journal volume & issue
-
Vol. 11,
no. 1
pp. 1 – 20
Abstract
Crossing over is a critical process during meiosis, although the regulation of this process still remains somewhat elusive. Here, the authors show that PRR19 partners with CNTD1 to enable formation of crossover-specific recombination complexes in mouse germ cells.
