EVALUATION OF THE EXPRESSION OF TRANSCRIPTION, NEOANGIOGENESIS AND APOPTOSIS FACTORS IN CASE OF POSTOPERATIVE COMPLICATIONS IN PATIENTS WITH DIFFERENT PROGRESSION OF ORAL MUCOSA CANCER

Abstract

While studying the expression of transcription, neoangiogenesis and apoptosis factors in the tumour tissue and oral fluid of 141 patients with oral mucosa cancer T1-3N0-2M0, it was shown that oral mucosa cancer progression combined with postoperative purulent inflammatory complications were associated with a high level of transcription factors, enhanced translocation of hypoxia-inducible factor-1б in the core, high expression of vascular endothelial growth factor and activation of apoptosis in the tumour tissue. The revealed changes in the underlying disease progression have a reasonably greater severity.

Keywords

• oral mucosa cancer
• transcription factors
• vegf
• apoptosis
• tumour tissue
• oral fluid