Study of Prevalence and Some Immunological Characteristics of Cytomegalovirus Infections among Pregnant Women

Abstract

Cytomegalovirus1(CMV)i is one of the essential causes o of intrauterine contagions. The contagion is commonly asymptomatic in immunocompotent adults, but its import in various times elevated when it happens throughout pregnancy. Pregnant women with CMV i infection can be responsible for abortion or congenital malformation. This subject was aimed to estimate the prevalence of cytomegalovirus virus amid pregnant women in Babylon province and evaluation of some haematological and immunological parameters in women infected with CMV. The study was conducted on (145) pregnant women referred to the Babylon Teaching Hospital for Maternity and Children to investigate the prevalence of Cytomegalovirus in Babylon province. Overall of (145) pregnant women was contained in this study, CMV specific IgM and IgG antibody were detected by minividas-test. Blood hemoglobin (Hb) concentration, neutrophil and lymphocyte accounts were determinate. Single radial immune diffusion plates were used for assessment of C3 and C41 level in infected women. Among 145 pregnant women were evaluated for CMV, (95.1%) were positive toward I IgG and (4.1%) were positive toward I IgM. Most of CMV infections among women with age ranging between 20-29 years. It was found that there was a increase in the lymphocyte count and complement components C3 and decrease in the C4 level among CMV patients compared to control group, while haemoglobin and neutrophile level appeared normal. This study summarized that there are increasing seropositivity rate for r human cytomegalovirus amid pregnant women The prevalence of CMV was relatively high in our locality.

Keywords

• cmv
• igm
• igg. pregnant women
• babylon