Journal of Clinical and Scientific Research (Jan 2019)

A rare case of paediatric non-Hodgkin's lymphoma

  • D Bhargavi,
  • T Kannan,
  • K L Priyadarshini,
  • V Santhosh,
  • K M Ramprahlad,
  • B Sreekanth

DOI
https://doi.org/10.4103/JCSR.JCSR_20_18
Journal volume & issue
Vol. 8, no. 2
pp. 95 – 97

Abstract

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Anaplastic large cell lymphoma (ALCL) is a rare disease accounting for 10%–15% of all non-Hodgkin's lymphomas in children. It is distinguished from other lymphomas by their anaplastic cytology and constant membrane expression of the CD30 antigen. We report a 9-year-old boy presented with a left calf swelling. Biopsy from swelling revealed as small cell variant of anaplastic lymphoma kinase-positive ALCL. Staging with positron emission tomography–computed tomography showed lymph nodal and multiple extra-nodal involvement. The extra-nodal sites were lung, pancreas, bone, sphenoid sinus and muscles. He was started on ALCL-99 protocol.

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