Retroviral insertional mutagenesis identifies the del(5q) genes, CXXC5, TIFAB and ETF1, as well as the Wnt pathway, as potential targets in del(5q) myeloid neoplasms

• Angela Stoddart,
• Zhijian Qian,
• Anthony A. Fernald,
• Rachel J. Bergerson,
• Jianghong Wang,
• Theodore Karrison,
• John Anastasi,
• Elizabeth T. Bartom,
• Aaron L. Sarver,
• Megan E. McNerney,
• David A. Largaespada,
• Michelle M. Le Beau

Affiliations

Angela Stoddart

Department of Medicine, University of Chicago, Chicago, IL, USA

Zhijian Qian

Department of Medicine, and University of Illinois Cancer Center, University of Illinois at Chicago, Chicago, IL, USA

Anthony A. Fernald

Department of Medicine, University of Chicago, Chicago, IL, USA

Rachel J. Bergerson

Department of Pediatrics, Masonic Cancer Center, University of Minnesota, Minneapolis, MN, USA

Jianghong Wang

Department of Medicine, University of Chicago, Chicago, IL, USA

Theodore Karrison

Department of Public Health Sciences, University of Chicago, Chicago, IL, USA;University of Chicago Medicine Comprehensive Cancer Center, Chicago, IL, USA

John Anastasi

University of Chicago Medicine Comprehensive Cancer Center, Chicago, IL, USA;Department of Pathology, University of Chicago, Chicago, IL, USA

Elizabeth T. Bartom

Department of Biochemistry and Molecular Genetics, Northwestern University Feinburg School of Medicine, Chicago, IL, USA

Aaron L. Sarver

Department of Pediatrics, Masonic Cancer Center, University of Minnesota, Minneapolis, MN, USA

Megan E. McNerney

University of Chicago Medicine Comprehensive Cancer Center, Chicago, IL, USA;Departments of Pathology and Pediatrics, and Institute for Genomics and Systems Biology, University of Chicago, Chicago, IL, USA

David A. Largaespada

Department of Pediatrics, Masonic Cancer Center, University of Minnesota, Minneapolis, MN, USA

Michelle M. Le Beau

Department of Medicine, University of Chicago, Chicago, IL, USA;University of Chicago Medicine Comprehensive Cancer Center, Chicago, IL, USA