Primary hyperparathyroidism clinical features on endocrinology in-patients clinic

Abstract

Aim. The analysis clinical features of primary hyperparathyroidism on endocrinology in-patients clinic. Materials and methods. Open retrospective study, included data of patients who were hospitalized at Kirov Regional Hospital with primary hyperparathyroidism from January 01, 2013 to December 31, 2016. Results and discussion. 23 patients were hospitalized. Their age is 24-78 years old (mediana 59 [52; 65] years old). There are 20 (87%) women, and 3 (13%) men. Manifest forms of primary hyperparathyroidism were detected in 18 (78.3%) patients, mild forms - in 5 (21.7%) patients. Pathological fracture had 7 (30.4%) patients including 3 (13%) vertebrae and hip fracture, urolithiasis had 10 (43.5%) persons. High blood calcium or parathyroma in ultra-sound were initially revealed in 8 (34.8%) patients 4 (50%) of them had manifest primary hyperparathyroidism. Period before diagnosis was 2 years and more in 10 (43.5%) patients. Conclusion. Clinical features of primary hyperparathyroidism are prevalence of manifest forms, late diagnosis, and high enough frequent of accidental reveal (including persons with representative symptoms).

Keywords

• primary hyperparathyroidism
• clinical features of primary hyperparathyroidism
• diagnosis of hyperparathyroidism