Associations of vascular calcification, calcium phosphate disturbances, FGF 23 and Matrix Gla protein with mortality of hemodialysis patients: one center cohort study

Petrauskiene Vaida; Vaiciuniene Ruta; Kuzminskis Vytautas; Ziginskiene Edita; Grazulis Saulius; Jonaitiene Egle; Skrodeniene Erika; Bumblyte Inga Arune

doi:10.2478/rrlm-2018-0034

Romanian Journal of Laboratory Medicine (Oct 2018)

Associations of vascular calcification, calcium phosphate disturbances, FGF 23 and Matrix Gla protein with mortality of hemodialysis patients: one center cohort study

Petrauskiene Vaida,
Vaiciuniene Ruta,
Kuzminskis Vytautas,
Ziginskiene Edita,
Grazulis Saulius,
Jonaitiene Egle,
Skrodeniene Erika,
Bumblyte Inga Arune

Affiliations

Petrauskiene Vaida: Department of Nephrology, Medical Academy, Lithuanian University of Health Sciences, Lithuania
Vaiciuniene Ruta: Department of Nephrology, Medical Academy, Lithuanian University of Health Sciences, Lithuania
Kuzminskis Vytautas: Department of Nephrology, Medical Academy, Lithuanian University of Health Sciences, Lithuania
Ziginskiene Edita: Department of Nephrology, Medical Academy, Lithuanian University of Health Sciences, Lithuania
Grazulis Saulius: Department of Nephrology, Medical Academy, Lithuanian University of Health Sciences, Lithuania
Jonaitiene Egle: Department of Radiology, Medical Academy, Lithuanian University of Health Sciences, Lithuania
Skrodeniene Erika: Department of Laboratory medicine, Medical Academy, Lithuanian University of Health Sciences, Lithuania
Bumblyte Inga Arune: Department of Nephrology, Medical Academy, Lithuanian University of Health Sciences, Lithuania

DOI: https://doi.org/10.2478/rrlm-2018-0034
Journal volume & issue: Vol. 26, no. 4
pp. 451 – 460

Abstract

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Background and objectives: Vascular calcification (VC) is one of the factors associated with mortality in hemodialysis (HD) patients. The purpose of the study was to assess associations between prevalent VC and disturbances of calcium-phosphate metabolism as well as changes in vitamin D (25(OH)D), FGF 23 and MGP levels and to evaluate the possible impact of VC and changes of these biomarkers on survival in HD patients.

Published in Romanian Journal of Laboratory Medicine

ISSN: 2284-5623 (Online)
Publisher: Sciendo
Country of publisher: Poland
LCC subjects: Medicine
Website: https://sciendo.com/journal/RRLM

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Abstract

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