Determination of Sigma metric based on various TEa sources for CBC parameters: the need for Sigma metrics harmonization

Abstract

The application of Sigma metrics can be used for assessing the performance of diagnostic laboratories. Clinical laboratories are confronted with the trouble of having to select the best and suitable quality specifications that are required for quality planning. In this regard, our study aims at evaluating the performance of Sysmex XN-1000 hematology analyzer by using Sigma metrics based on different total allowable error (TEa) source and to determine the effects of these variations in Sigma metric evaluation.

Keywords

• biological variation
• hematology (complete blood count)
• sigma metric
• total allowable error