DIAGNOSTIC VALUE OF IMMUNOLOGICAL EXAMINATION IN SPECIFYING A ROLE OF HERPESVIRUS INFECTION IN DEVELOPMENT OF HEMORRHAGIC VASCULITIS WITH RENAL IMPAIRMENT

Abstract

Determination of etiologic and\or trigger role of herpesvirus infection, immune disorders in development of hemorrhagic vasculitis with renal impairment is useful for optimizing treatment of such patients. Detection of herpes virus activation markers and disorders of immune status in the development of hemorrhagic vasculitis with renal impairment substantiates complex therapeutic schedules including antiviral and immunocorrection drugs. A timely and purposeful antiviral therapy promotes earlier fading of clinical signs typical to hemorrhagic vasculitis. A long-lasting activation of humoral immune system in combination with urinary syndrome suggests a higher risk of immune nephropathy progression, thus requiring long-termmonitoring and implementation of appropriate therapy.

Keywords

• herpes virus infection
• hemorrhagic vasculitis
• glomerulonephritis
• immune status
• antiviral therapy
• immunotherapy