Nature Communications (Sep 2020)
Serological identification of SARS-CoV-2 infections among children visiting a hospital during the initial Seattle outbreak
- Adam S. Dingens,
- Katharine H. D. Crawford,
- Amanda Adler,
- Sarah L. Steele,
- Kirsten Lacombe,
- Rachel Eguia,
- Fatima Amanat,
- Alexandra C. Walls,
- Caitlin R. Wolf,
- Michael Murphy,
- Deleah Pettie,
- Lauren Carter,
- Xuan Qin,
- Neil P. King,
- David Veesler,
- Florian Krammer,
- Jane A. Dickerson,
- Helen Y. Chu,
- Janet A. Englund,
- Jesse D. Bloom
Affiliations
- Adam S. Dingens
- Basic Sciences and Computational Biology, Fred Hutchinson Cancer Research Center
- Katharine H. D. Crawford
- Basic Sciences and Computational Biology, Fred Hutchinson Cancer Research Center
- Amanda Adler
- Division of Infectious Disease, Seattle Children’s Hospital
- Sarah L. Steele
- Division of Infectious Disease, Seattle Children’s Hospital
- Kirsten Lacombe
- Division of Infectious Disease, Seattle Children’s Hospital
- Rachel Eguia
- Basic Sciences and Computational Biology, Fred Hutchinson Cancer Research Center
- Fatima Amanat
- Graduate School of Biomedical Sciences, Icahn School of Medicine at Mount Sinai
- Alexandra C. Walls
- Department of Biochemistry, University of Washington
- Caitlin R. Wolf
- Division of Allergy and Infectious Diseases, University of Washington
- Michael Murphy
- Institute for Protein Design, University of Washington
- Deleah Pettie
- Institute for Protein Design, University of Washington
- Lauren Carter
- Institute for Protein Design, University of Washington
- Xuan Qin
- Division of Infectious Disease, Seattle Children’s Hospital
- Neil P. King
- Department of Biochemistry, University of Washington
- David Veesler
- Department of Biochemistry, University of Washington
- Florian Krammer
- Department of Microbiology, Icahn School of Medicine at Mount Sinai
- Jane A. Dickerson
- Division of Infectious Disease, Seattle Children’s Hospital
- Helen Y. Chu
- Division of Allergy and Infectious Diseases, University of Washington
- Janet A. Englund
- Division of Infectious Disease, Seattle Children’s Hospital
- Jesse D. Bloom
- Basic Sciences and Computational Biology, Fred Hutchinson Cancer Research Center
- DOI
- https://doi.org/10.1038/s41467-020-18178-1
- Journal volume & issue
-
Vol. 11,
no. 1
pp. 1 – 6
Abstract
COVID-19 disease is less common in children than adults, but the extent to which SARS-CoV-2 infections are missed through symptom-driven testing is not well understood. In this study, the authors show that approximately 1% of children seeking care for reasons other than COVID-19 at a Seattle hospital in March/April 2020 were seropositive for SARS-CoV-2.
