2,3,5,6-Tetrafluoro-[<i>N</i>-(3-aminopropyl)-ε-caprolactam]-4-pyridine

Abstract

The title compound was synthesized at a near-quantitative yield using the nucleophilic aromatic substitution of 1,8-diazabicyclo[5.4.0]undec-7-ene (DBU) with perfluoropyridine (PFP). The purity and structure were determined by NMR (1H, 13C, 19F), GC-EIMS, and single-crystal X-ray crystallography.

Keywords

• organo-fluorine
• pyridine
• pentafluoropyridine
• 1,8-diazabicyclo[5.4.0]undec-7-ene (DBU)
• nucleophilic aromatic substitution