Case of lethal outcome of an infant due to COVID-19

Abstract

The article presents clinical data and the results of a detailed pathology changes in a 2-month-old infant who died from a coronavirus infection, confirmed by the results of in vivo PCR and morphological examination, which included the detection of the SARS-Cov-2 spike antigen. Histological examination in the lungs, as well as in the brain revealed cytoproliferative and cytopathic changes similar to those described in coronavirus infection in adults, while other characteristic for them lesions were not determined. The unfavorable course of COVID-19 was facilitated by an activated intrauterine infection, mycoplasmosis or chlamydiosis according to morphological data.

Keywords

• covid-19 in infants
• morphological features
• immunohistochemistry
• spike antigen