Dataset on the synthesis and characterization of boron fenbufen and its F-18 labeled homolog

Chun-Nan Yeh; Chi-Wei Chang; Yi-Hsiu Chung; Shi-Wei Tien; Yong-Ren Chen; Tsung-Wen Chen; Ying-Cheng Huang; Hsin-Ell Wang; You-Cheng Chou; Ming-Huang Chen; Kun-Chun Chiang; Wen-Sheng Huang; Chung-Shan Yu

Data in Brief (Dec 2017)

Dataset on the synthesis and characterization of boron fenbufen and its F-18 labeled homolog

Chun-Nan Yeh,
Chi-Wei Chang,
Yi-Hsiu Chung,
Shi-Wei Tien,
Yong-Ren Chen,
Tsung-Wen Chen,
Ying-Cheng Huang,
Hsin-Ell Wang,
You-Cheng Chou,
Ming-Huang Chen,
Kun-Chun Chiang,
Wen-Sheng Huang,
Chung-Shan Yu

Affiliations

Chun-Nan Yeh: Department of Surgery, Liver Research Center, Chang-Gung Memorial Hospital at Linkou, Chang Gung University, Taiwan
Chi-Wei Chang: Department of Nuclear Medicine, Veterans General Hospital at Taipei, Taiwan
Yi-Hsiu Chung: Center for Advanced Molecular Imaging and Translation, Chang Gung Memorial Hospital, Taiwan
Shi-Wei Tien: Department of Biomedical Engineering and Environmental Sciences, National Tsinghua University, Hsinchu 300, Taiwan
Yong-Ren Chen: Department of Biomedical Engineering and Environmental Sciences, National Tsinghua University, Hsinchu 300, Taiwan
Tsung-Wen Chen: Department of Surgery, Liver Research Center, Chang-Gung Memorial Hospital at Linkou, Chang Gung University, Taiwan
Ying-Cheng Huang: Department of Neurosurgery, Chang-Gung Memorial Hospital at Linkou, Chang Gung University, Taiwan
Hsin-Ell Wang: Department of Biomedical Imaging and Radiological Sciences, National Yang-Ming University, Taipei, Taiwan
You-Cheng Chou: Department of Biomedical Engineering and Environmental Sciences, National Tsinghua University, Hsinchu 300, Taiwan
Ming-Huang Chen: Department of Medical Radiology, Yang-Ming University at Taipei, Taiwan
Kun-Chun Chiang: Department of Surgery, Chang-Gung Memorial Hospital at Keelung, Chang Gung University, Taiwan
Wen-Sheng Huang: Department of Nuclear Medicine, Veterans General Hospital at Taipei, Taiwan
Chung-Shan Yu: Department of Biomedical Engineering and Environmental Sciences, National Tsinghua University, Hsinchu 300, Taiwan; Institute of Nuclear Engineering and Science, National Tsing-Hua University, Hsinchu 300, Taiwan

Journal volume & issue: Vol. 15
pp. 174 – 202

Abstract

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The data presented in this article are related to the research article entitled âSynthesis and Characterization of Boron Fenbufen and its F-18 Labeled Homolog for Boron Neutron Capture Therapy of COX-2 Overexpressed Cholangiocarcinomaâ. The contents of the data article include 1) the set up for performing in vitro binding assay, 2) 1H-, 13C- and 19F-NMR of compounds described in main text, 3) HPLC chromatogram of the fluorination mixtures, 4) data of in vitro stability test, cell survival assay, western blot and PCR analysis, 5) the modules for fixing the two CCA rats for BNCT, and 6) bar diagram for tumor reduction using [18F]FDG-PET 24Â h post treatment with BNCT. Keywords: Setup, NMR spectra, Coupling constant, Binding, Survival

Published in Data in Brief

ISSN: 2352-3409 (Online)
Publisher: Elsevier
Country of publisher: United States
LCC subjects: Medicine: Medicine (General): Computer applications to medicine. Medical informatics; Science: Science (General)
Website: http://www.journals.elsevier.com/data-in-brief/

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