Evaluation of retinal microvasculature in exotropia with abnormal binocular vision by optical coherence tomography angiography

Abstract

Abstract Background To explore the retinal microvasculature in large-angle concomitant exotropia patients with abnormal binocular vision using optical coherence tomography angiography (OCTA) analysis. Methods OCTA images of 52 healthy and 100 strabismic eyes were analyzed to quantify the retinal thickness (RT), superficial capillary plexus (SCP), deep capillary plexus (DCP), and foveal avascular zone (FAZ). Paired t-tests were performed to compare differences between the two groups, the dominant eye and the deviated eye in the exotropia group, respectively. A p-value 0.01). Conclusions The study showed that OCTA revealed subnormal DCP in patients with large-angle exotropia and abnormal binocularity which may be related to retinal suppression. Changes in the macular microvasculature may provide valuable insights into the development of strabismus. Further studies are needed to determine the clinical relevance of this finding. Trial registration This trial is registered as ChiCTR2100052577 at www.Chictr.org.cn .

Keywords

• Large-angle concomitant exotropia
• Optical coherence tomography angiography
• Macular microvasculature
• Binocular vision