Green, lithium salt-free synthesis of 2-alkylated 1,4-benzenediols in hydroalcoholic media

Abstract

Herein, we describe an efficient, green, and lithium salt-free synthesis of 2-substituted 1,4-benzenediol in water/ethanol as solvent and potassium carbonate as a base. Optimized reaction time, the required equivalent of base and the observed solvent effect are reported.

Keywords

• Hydroalcoholic media
• lithium salt free
• green method