Indian Journal of Ophthalmology (Jan 2013)
Corneal arcus and xanthomas in homozygous familial hypercholesterolemia: First report from China
- Xin Meng,
- Jie Lin,
- Xinxiao Gao,
- Jia Guo,
- Chen Xin,
- Jun Wang
Affiliations
- Xin Meng
- Jie Lin
- Xinxiao Gao
- Jia Guo
- Chen Xin
- Jun Wang
- DOI
- https://doi.org/10.4103/0301-4738.118456
- Journal volume & issue
-
Vol. 61,
no. 12
pp. 770 – 771
Abstract
We report the case of a 12-year-old male who developed corneal arcus and multiple skin lesions with a 10-year history of xanthomas. The lesions appeared over his fingers, hands, elbows, knees, buttocks and feet. Laboratory studies showed a total serum cholesterol level of 752.1 mg/dL; a triglyceride level of 96.6 mg/dL; a low-density lipoprotein cholesterol level of 661.3 mg/dL. Findings were consistent with homozygous familial hypercholesterolemia. To our knowledge, this is the first such case to be reported from China.
Keywords
- Amblyopia
- nasolacrimal duct obstruction
- probing
- Duane syndrome
- esotropia
- strabismus
- Bevacizumab
- mitochondrial function
- microvascular endothelial cells
- neurosensory retinal cells
- retinal pigment epithelial cells
- tissue culture
- Clinical donor tissue grading
- death to enucleation time
- death to preservation time
- eye bank specular microscopy
- optimizing donor tissue utilization
- DCR
- endodiathermy bipolar probe
- nasolacrimal duct obstruction
- recanalize
- Age-related macular degeneration
- carotenoids
- cross-sectional studies
- lutein
- Children
- GDx variable corneal compensation
- Indian
- normal
- retinal nerve fiber layer thickness
- Biological amniotic membrane
- 5-fluorouracil
- retina
- trabeculectomy
- Clinical features
- complications
- etiology
- retinal vasculitis
- Thailand
- Coloboma of the choroid
- coloboma optic disc
- indo cyanine green angiography
- vascular pattern
- Aphakia
- inadequate capsular support
- pediatric aphakia
- secondary intraocular lens implantation
- steel suture
- trans-scleral fixation
- vanadium steel
- Drug reaction
- drug-induced
- ranibizumab
- subacute cutaneous lupus erythematosus
- Prevalence
- rapid
- rapid assessment of refractive errors
- spectacles use
- uncorrected refractive errors
- visual impairment
- Bitemporal hemianopia
- Traumatic chiasmal syndrome
- visual field
- Phaeohyphomycosis
- pigmented fungi
- subretinal abscess
- subretinal biopsy
- Brimonidine
- combination
- glaucoma
- intraocular pressure
- timolol
- Congenital
- dermis fat graft
- orbital
- teratoma
- Familial hypercholesterolemia
- corneal arcus
- xanthomas