Statistical Analysis of Lipid Profiles Associated with Coronary Heart Disease in Erbil City-Iraq

Abstract

Background and objectives: Coronary heart disease (CHD) is one of the most prevalent diseases worldwide. The primary risk factor for coronary heart disease (CHD) lies in the presence of hypertension, elevated levels of triglycerides (TG), total cholesterol (TC), and low-density lipoprotein (LDL) in the bloodstream. Furthermore, a reduction in high-density lipoprotein (HDL) levels is linked to an elevated risk of cardiovascular disease-related mortality. The current retrospective study was undertaken to evaluate the alterations in the lipid profile of patients with CHD. Methods: The current survey involved collecting data from 867 patients diagnosed with acute or severe CHD, with an average age of 48.38± 0.503. In addition, the study included 850 healthy controls whose average age was 47.22±1.234. The serum levels of TC, HDL, LDL, and TG were obtained from Zanko Hospital in Erbil city, Iraq. The comparison between the recorded parameters of healthy controls and patients was conducted using the t-test function in GraphPad Prism 6.0. Results: The lipid profile consisted of measurements for TC, LDL, HDL, and TG. The TC levels were notably higher in cases of CHD in individuals under 40 years old compared to controls. Moreover, there was a notable rise in TG levels among individuals with CHD aged 40-60, in contrast to the control group. Conversely, there was no significant difference in the levels of HDL and LDL between the cases and control group. Conclusions: There was a significant difference in TC and TG levels between cases and controls in certain groups, while other lipid profiles did not show significant changes.

Keywords

• cardiovascular disease,
• cholesterol,
• coronary heart diseases,
• lipid profile,
• triglycerides