The Clinical Respiratory Journal (Aug 2024)

Primary Lung Squamous Cell Carcinoma With Intestinal Metastasis: A Case Report and Literature Review

  • Jin Tao,
  • Zhiqiang Wu,
  • Rongfei Huang,
  • Jun Li,
  • Tiewei Xu,
  • Yujie Gao,
  • Weikun Jia,
  • Hu Chen

DOI
https://doi.org/10.1111/crj.13817
Journal volume & issue
Vol. 18, no. 8
pp. n/a – n/a

Abstract

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ABSTRACT Lung squamous cell carcinoma (LUSC) is characterized by a high rate of metastasis and recurrence, leading to a poor prognosis for affected patients. Intestinal metastasis of LUSC is a rare clinical occurrence. Treatment options for LUSC patients with intestinal metastasis are limited, and no standard therapy guidelines exist for managing these cases. In this review, we discuss the clinical features, diagnosis, and treatment of LUSC patients with intestinal metastasis and present a rare case of LUSC with intestinal metastasis. We describe a patient who presented with a severe cough and chest pain and diagnosed with LUSC and bone tumor. Initially, the primary LUSC and bone tumor were controlled with standard treatments. However, the primary LUSC reoccurred shortly after treatment, this time with intestinal metastasis, for which effective treatments are lacking. Our observation from the case suggests that LUSC metastasizing to intestinal tract is associated with a poorer prognosis.

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