Nature Communications (Sep 2021)

A deep-learning framework for multi-level peptide–protein interaction prediction

  • Yipin Lei,
  • Shuya Li,
  • Ziyi Liu,
  • Fangping Wan,
  • Tingzhong Tian,
  • Shao Li,
  • Dan Zhao,
  • Jianyang Zeng

DOI
https://doi.org/10.1038/s41467-021-25772-4
Journal volume & issue
Vol. 12, no. 1
pp. 1 – 10

Abstract

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Peptide-protein interactions play fundamental roles in cellular processes and are crucial for designing peptide therapeutics. Here, the authors present a deep learning framework for simultaneously predicting peptide-protein interactions and identifying peptide binding residues involved in the interactions.