Nature Communications (Sep 2019)

A highly dynamic F-actin network regulates transport and recycling of micronemes in Toxoplasma gondii vacuoles

  • Javier Periz,
  • Mario Del Rosario,
  • Alexandra McStea,
  • Simon Gras,
  • Colin Loney,
  • Lin Wang,
  • Marisa L. Martin-Fernandez,
  • Markus Meissner

DOI
https://doi.org/10.1038/s41467-019-12136-2
Journal volume & issue
Vol. 10, no. 1
pp. 1 – 16

Abstract

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Replication of Toxoplasma gondii requires replication and distribution of essential organelles such as micronemes. Here, Periz et al. show that micronemes are recycled from the mother to the forming daughter cells using a highly dynamic F-actin network that supports multidirectional vesicle transport.