Association of maxillary sinus mucosal thickening and peri-apical lesion in cone-beam computed tomographic images: A systematic review and meta-analysis

Abstract

Maxillary sinusitis is one of the most common pathologies worldwide and a substantial cause of sinus mucosal thickening. Around 10–86% of maxillary sinusitis reported odontogenic origin. A systematic review and meta-analysis were designed and aimed to evaluate the association of maxillary sinus mucosal thickening and peri-apical lesions using cone-beam computed tomography (CBCT). An extensive bibliographic search with directed vocabulary (MeSH terms in PubMed) and free-text terms were used in databases such as PubMed, Google Scholar, and EBSCO. A total one 8427 articles were identified through the electronic database [Pubmed (34), Ebscohost (0), Google Scholar]. For the meta-analysis, six articles were selected following PRISMA guidelines. One of the major causes of sinus mucosal thickening is reported to be periapical lesions, and the results of the review and meta-analysis concluded that maxillary mucosal sinus thickening was associated with periapical lesions evaluated by CBCT. The results put forward by this review are of utmost importance in treating patients with regenerative and implant procedures related to the posterior maxillary region.

Keywords

• cbct
• maxillary sinus mucosal thickening
• maxillary sinusitis
• peri-apical lesions