Mucosal immunology and models of mucosal HIV infection

Abstract

The mucosa associated lymphoid tissue regulates and coordinates immune responses against mucosal pathogens. Mucosal tissues are the major targets exposed to HIV during transmission. In this paper we describe in vitro models of HIV mucosal infection using human explants to investigate target cells within this tissue.

Keywords

• mucosal immunology
• HIV
• immunity to HIV
• mucosa associated lymphoid tissue