Diagnostics (Sep 2024)

Radiofrequency Echographic Multi Spectrometry (REMS) Technology for Bone Health Status Evaluation in Kidney Transplant Recipients

  • Angelo Fassio,
  • Giovanni Adami,
  • Stefano Andreola,
  • Pietro Manuel Ferraro,
  • Paola Pisani,
  • Fiorella Anna Lombardi,
  • Ombretta Viapiana,
  • Maurizio Rossini,
  • Chiara Caletti,
  • Giovanni Gambaro,
  • Matteo Gatti,
  • Davide Gatti

DOI
https://doi.org/10.3390/diagnostics14182106
Journal volume & issue
Vol. 14, no. 18
p. 2106

Abstract

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Background: A significant loss in bone density and strength occurs during the post-renal-transplant period with higher susceptibility to fracture. The study aims to compare the performance of the Radiofrequency Echographic Multi Spectrometry (REMS) in the bone mineral density assessment with the conventional dual-energy X-ray absorptiometry (DXA) in a cohort of kidney transplant recipients (KTR). Methods: A cohort of 40 patients underwent both DXA and REMS examinations on the lumbar spine and/or proximal femur. The paired t-test was used to compare DXA and REMS measurements; the chi-square test was used to compare the prevalence of osteoporosis/osteopenia. The agreement between the two techniques was assessed through Spearman’s correlation. Results: As expected, most KTR patients were osteopenic or osteoporotic with both REMS and DXA (86.5% and 81% for the femur; 88% and 65% for the lumbar spine p p p Conclusions: The study demonstrates the exchangeability of the two techniques on the proximal femur in KTR and a higher diagnostic accuracy of REMS at the spine level than DXA.

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