Lipopeptide Antibiotics Derived from Polymyxin B with a Broad Spectrum of Activity: Membrane Interaction

Yolanda Cajal; Roser Segovia; Angeles Manresa; Ariadna Grau-Campistany; Francesc Rabanal

doi:10.3390/proceedings1060654

Proceedings (Oct 2017)

Lipopeptide Antibiotics Derived from Polymyxin B with a Broad Spectrum of Activity: Membrane Interaction

Yolanda Cajal,
Roser Segovia,
Angeles Manresa,
Ariadna Grau-Campistany,
Francesc Rabanal

Affiliations

Yolanda Cajal: Department of Pharmacy, Pharmaceutical Technology and Physical Chemistry, Faculty of Pharmacy and Food Sciences, University of Barcelona, 08028 Barcelona, Spain
Roser Segovia: Section of Organic Chemistry, Department of Inorganic and Organic Chemistry, Faculty of Chemistry, University of Barcelona, 08028 Barcelona, Spain
Angeles Manresa: Laboratory of Microbiology, Faculty of Pharmacy and Food Sciences, University of Barcelona, 08028 Barcelona, Spain
Ariadna Grau-Campistany: Department of Pharmacy, Pharmaceutical Technology and Physical Chemistry, Faculty of Pharmacy and Food Sciences, University of Barcelona, 08028 Barcelona, Spain
Francesc Rabanal: Section of Organic Chemistry, Department of Inorganic and Organic Chemistry, Faculty of Chemistry, University of Barcelona, 08028 Barcelona, Spain

DOI: https://doi.org/10.3390/proceedings1060654
Journal volume & issue: Vol. 1, no. 6
p. 654

Abstract

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Antimicrobial peptides offer a new class of therapeutic agents to which bacteria may not be able to develop genetic resistance, since they act on the lipid component of the cell membranes [1]. [...]

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Published in Proceedings

ISSN: 2504-3900 (Online)
Publisher: MDPI AG
Country of publisher: Switzerland
LCC subjects: General Works
Website: http://www.mdpi.com/journal/proceedings

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