Communications Biology (Sep 2021)
In vitro CSC-derived cardiomyocytes exhibit the typical microRNA-mRNA blueprint of endogenous cardiomyocytes
- Mariangela Scalise,
- Fabiola Marino,
- Luca Salerno,
- Teresa Mancuso,
- Donato Cappetta,
- Antonella Barone,
- Elvira Immacolata Parrotta,
- Annalaura Torella,
- Domenico Palumbo,
- Pierangelo Veltri,
- Antonella De Angelis,
- Liberato Berrino,
- Francesco Rossi,
- Alessandro Weisz,
- Marcello Rota,
- Konrad Urbanek,
- Bernardo Nadal-Ginard,
- Daniele Torella,
- Eleonora Cianflone
Affiliations
- Mariangela Scalise
- Department of Experimental and Clinical Medicine, Magna Graecia University
- Fabiola Marino
- Department of Experimental and Clinical Medicine, Magna Graecia University
- Luca Salerno
- Department of Experimental and Clinical Medicine, Magna Graecia University
- Teresa Mancuso
- Department of Medical and Surgical Sciences, Magna Graecia University
- Donato Cappetta
- Department of Experimental Medicine, University of Campania “L. Vanvitelli”
- Antonella Barone
- Department of Experimental and Clinical Medicine, Magna Graecia University
- Elvira Immacolata Parrotta
- Department of Medical and Surgical Sciences, Magna Graecia University
- Annalaura Torella
- Department of Precision Medicine, University of Campania “Luigi Vanvitelli”
- Domenico Palumbo
- Department of Medicine, Surgery and Dentistry ‘Scuola Medica Salernitana’, University of Salerno
- Pierangelo Veltri
- Department of Medical and Surgical Sciences, Magna Graecia University
- Antonella De Angelis
- Department of Experimental Medicine, University of Campania “L. Vanvitelli”
- Liberato Berrino
- Department of Experimental Medicine, University of Campania “L. Vanvitelli”
- Francesco Rossi
- Department of Experimental Medicine, University of Campania “L. Vanvitelli”
- Alessandro Weisz
- Department of Medicine, Surgery and Dentistry ‘Scuola Medica Salernitana’, University of Salerno
- Marcello Rota
- Department of Physiology, New York Medical College
- Konrad Urbanek
- Department of Experimental and Clinical Medicine, Magna Graecia University
- Bernardo Nadal-Ginard
- Department of Medical and Surgical Sciences, Magna Graecia University
- Daniele Torella
- Department of Experimental and Clinical Medicine, Magna Graecia University
- Eleonora Cianflone
- Department of Medical and Surgical Sciences, Magna Graecia University
- DOI
- https://doi.org/10.1038/s42003-021-02677-y
- Journal volume & issue
-
Vol. 4,
no. 1
pp. 1 – 16
Abstract
Scalise et al. examine the mRNAome and miRNAome of cardiomyocytes differentiated from murine adult cardiac stem cells (CSCs). Their results show that the differentiation process follows a trajectory of miRNA/mRNA expression that resembles that of adult cardiomyocytes.
