Layer-by-layer biofunctionalization of nanostructured porous silicon for high-sensitivity and high-selectivity label-free affinity biosensing

Abstract

In label-free biosensing surface functionalisation is a complex issue that can affect sensing performance. Here, the authors report on an electrostatic layer-by-layer technique to functionalize a surface and demonstrate this technique using biotinylated polymer for streptavidin detection in saliva.