H2AK121ub in Arabidopsis associates with a less accessible chromatin state at transcriptional regulation hotspots

Abstract

Polycomb Group complexes maintain gene repression through the incorporation of H2AK121ub and H3K27me3. Here, the authors show that H2AK121ub marks less accessible but transcriptionally permissive chromatin, while H3K27me3 enforces a repressed transcriptionally less-permissive state.