Trehalose improves the movement ability of Aβarc Drosophila by restoring the damaged mitochondria

Li Liangxian; Huang Zhiheng; Wu Mingli; Li Xia; Xiao Bo; Yao Dong; Mo Biwen

doi:10.1515/tnsci-2022-0338

Translational Neuroscience (Apr 2024)

Trehalose improves the movement ability of Aβarc Drosophila by restoring the damaged mitochondria

Li Liangxian,
Huang Zhiheng,
Wu Mingli,
Li Xia,
Xiao Bo,
Yao Dong,
Mo Biwen

Affiliations

Li Liangxian: Department of Respiratory and Critical Care Medicine, The Second Affiliated Hospital of Guilin Medical University, Guilin, 541199, China
Huang Zhiheng: Department of Respiratory and Critical Care Medicine, The Second Affiliated Hospital of Guilin Medical University, Guilin, 541199, China
Wu Mingli: Guangxi Key Laboratory of Brain and Cognitive Neuroscience, Guilin Medical University, Guilin, 541199, China
Li Xia: Guangxi Key Laboratory of Brain and Cognitive Neuroscience, Guilin Medical University, Guilin, 541199, China
Xiao Bo: Laboratory of Respiratory Disease, Affiliated Hospital of Guilin Medical University, Guilin, 541002, China
Yao Dong: Department of Respiratory and Critical Care Medicine, The Second Affiliated Hospital of Guilin Medical University, Guilin, 541199, China
Mo Biwen: Department of Respiratory and Critical Care Medicine, The Second Affiliated Hospital of Guilin Medical University, Guilin, 541199, China

DOI: https://doi.org/10.1515/tnsci-2022-0338
Journal volume & issue: Vol. 15, no. 1
pp. 505 – 17

Abstract

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The deposition of Aβ42 has been regarded as one of the important pathological features of Alzheimer’s disease (AD). However, drug development for Aβ42 toxicity has been progressed slowly.

Published in Translational Neuroscience

ISSN: 2081-6936 (Online)
Publisher: De Gruyter
Country of publisher: Poland
LCC subjects: Medicine: Internal medicine: Neurosciences. Biological psychiatry. Neuropsychiatry
Website: http://www.degruyter.com/view/j/tnsci

About the journal

Abstract

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