The global diversity of Haemonchus contortus is shaped by human intervention and climate

G. Sallé; S. R. Doyle; J. Cortet; J. Cabaret; M. Berriman; N. Holroyd; J. A. Cotton

doi:10.1038/s41467-019-12695-4

Nature Communications (Oct 2019)

The global diversity of Haemonchus contortus is shaped by human intervention and climate

G. Sallé,
S. R. Doyle,
J. Cortet,
J. Cabaret,
M. Berriman,
N. Holroyd,
J. A. Cotton

Affiliations

G. Sallé: Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton
S. R. Doyle: Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton
J. Cortet: INRA - U. Tours, UMR 1282 ISP Infectiologie et Santé Publique, Centre de recherche Val de Loire
J. Cabaret: INRA - U. Tours, UMR 1282 ISP Infectiologie et Santé Publique, Centre de recherche Val de Loire
M. Berriman: Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton
N. Holroyd: Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton
J. A. Cotton: Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton

DOI: https://doi.org/10.1038/s41467-019-12695-4
Journal volume & issue: Vol. 10, no. 1
pp. 1 – 14

Abstract

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Based on single worm whole genome sequencing, the authors here characterise the global evolution of the gastrointestinal parasite Haemonchus contortus and identify genes that play a role in drug resistance as well as climate-driven adaptations involving an epigenetic regulator.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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