Romanian Journal of Oral Rehabilitation (Sep 2024)

THE ANTI-INFLAMMATORY EFFECTS OF ASPIRIN IN THE TREATMENT OF GUM DISEASES

  • Gabi Topor,
  • Riana Maria Huzum,
  • Doriana Agop Forna,
  • Mălina Iris Maftei,
  • Simona Claudia Stefan

DOI
https://doi.org/10.6261/RJOR.2024.3.16.63
Journal volume & issue
Vol. 16, no. 3
pp. 616 – 628

Abstract

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This study examines the use of aspirin in dentistry, focusing on the treatment of gingival and periodontal diseases. Aspirin, known for its anti-inflammatory, analgesic and anticoagulant properties, is widely used in medicine, but its application in dentistry requires a thorough understanding of the associated benefits and risks. The review discusses aspirin’s mechanisms of action, its impact on periodontal health at the cellular and molecular level, and the potential for the development of topical formulations to minimize side effects. Current studies and the need for long-term research to evaluate the efficacy and safety of aspirin are also addressed. The paper identifies significant gaps in the existing literature, including the need to investigate drug interactions and tailor treatment to individual patient characteristics. In conclusion, aspirin has significant potential to improve the management of periodontal disease, but further investigation is needed to optimize the treatment protocol and ensure its safe use in dental practice.

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