Новые технологии (Jun 2019)

Production technology and functional orientation of biologically active additive for regulation of metabolic disorders in bone injury

  • B. Tohiriyon,
  • A. A. Vekovtsev,
  • V. M. Poznyakovsky

DOI
https://doi.org/10.24411/2072-0920-2019-10211
Journal volume & issue
Vol. 0, no. 2
pp. 108 – 117

Abstract

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An innovative technology and adjustable parameters for the production of a new vitamin-mineral complex for the regulation of metabolic disorders in bone injuries have been developed. The controlled production parameters include: mixture preparation (parts 1, 2) for encapsulation - 1 hour per 100 kg, sieving the mixture through a 1 mm sieve, mixing parts 1 and 2 for 60 minutes, pressing the capsule mass on ZANASI 40E capsule machine with working pressure of 50 n. Innovative technological solutions allow us to sort out prescription ingredients, according to their chemical and pharmacological incompatibility, to deliver them consistently to different parts of the gastrointestinal tract at a given speed. The specified functional orientation is complemented by biochemical and pharmacological characteristics of prescription components and their synergistic properties in relation to metabolic processes in bone injuries, which helps to substantiate scientifically qualitative and quantitative composition of a new vitamin-mineral complex. The quality indicators of the new specialized complex have been studied, and periods and modes of storage during production and storage have been determined. The nutritional value has been established , that determines the functional orientation of the vitamin-mineral complex, which is confirmed by the results of clinical studies. Production tests have been conducted at the enterprises of «Art Life» Scientific Production Association (Tomsk).

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