Медицинская иммунология (Jul 2014)

TRANSFORMING GROWTH FACTOR-BETA-1 BY DIFFERENT CLINICAL COURSE OF ISCHEMIC HEART DISEASE AFTER CORONARY ARTERY BYPASS GRAFTING SURGERY

  • K. V. Korzhenevskaya,
  • N. A. Gavrischeva,
  • A. V. Panov,
  • T. P. Ses’,
  • M. Z. Alugishvili,
  • V. V. Kozlov

DOI
https://doi.org/10.15789/1563-0625-2010-6-521-528
Journal volume & issue
Vol. 12, no. 6
pp. 521 – 528

Abstract

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The article presents data on the levels of transforming growth factor-beta-1 (TGF-β1) in blood serum and their correlation with clinical features of coronary artery disease in 130 patients with non-ST elevation acute coronary syndrome (non-ST ACS), who underwent coronary artery bypass grafting surgery (CABG), at different terms (6, 12, 24, 48 mo) following surgical intervention. It was revealed that a recurrent myocardial ischemia is associated with increased levels of TGF-β1. Following CABG, the TGF-β1 levels are significantly increasing, and reach their preoperative values by the end of observation period.

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