Analysis of biological characteristics of corneal endothelium in old patients with high myopia

Abstract

AIM: To analyze quantitatively the biological characteristics of corneal endothelium in old patients of high myopia with non-contact automatic corneal endothelial microscope.METHODS:A total of 189 old patients(197 eyes)were divided into the high myopia group and the normal control group according to refractive diopter, in which the former 98 cases(103 eyes), the latter 91 cases(94 eyes). The hexagonal cell(6A), the coefficient of variation(CV), the average cell area(AVE), the average cell density(CD)and the central corneal thickness(CCT)were measured by non-contact automatic corneal endothelium. SPSS 14.0 software was used to analyze their percentage. Z-test was used to compare the mean and Chi-square test was used to compare the rate in between. RESULTS: The average cell density in high myopia patients decreased, but there were 14 eyes >3 000/mm2, 11 eyes 2 and 78 eyes in the 2 000～3 000/mm2, there were each 0 eye, 3 eyes and 91 eyes respectively in the normal control group. There was statistically significant difference between high myopia group and control(χ2=19.11, PPP>0.05). CONCLUSION: There will provide a reference valuable for clinical surgeon. Because according to the changes of parameters and morphology of the corneal endothelial cells, we can understand the repair ability, to predict the consequence of the treatment, in order to determine the design and the choice of a surgical.

Keywords

• high myopia
• central corneal thickness
• corneal endothelium