Chromothripsis is linked to TP53 alteration, cell cycle impairment, and dismal outcome in acute myeloid leukemia with complex karyotype
Frank G. Rücker,
Anna Dolnik,
Tamara J. Blätte,
Veronica Teleanu,
Aurélie Ernst,
Felicitas Thol,
Michael Heuser,
Arnold Ganser,
Hartmut Döhner,
Konstanze Döhner,
Lars Bullinger
Affiliations
Frank G. Rücker
Department of Internal Medicine III, University Hospital of Ulm, Albert-Einstein-Allee 23, Germany
Anna Dolnik
Department of Internal Medicine III, University Hospital of Ulm, Albert-Einstein-Allee 23, Germany
Tamara J. Blätte
Department of Internal Medicine III, University Hospital of Ulm, Albert-Einstein-Allee 23, Germany
Veronica Teleanu
Department of Internal Medicine III, University Hospital of Ulm, Albert-Einstein-Allee 23, Germany
Aurélie Ernst
Division of Molecular Genetics, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany
Felicitas Thol
Department of Hematology, Hemostasis, Oncology, and Stem Cell Transplantation, Hannover Medical School, Berlin, Germany
Michael Heuser
Department of Hematology, Hemostasis, Oncology, and Stem Cell Transplantation, Hannover Medical School, Berlin, Germany
Arnold Ganser
Department of Hematology, Hemostasis, Oncology, and Stem Cell Transplantation, Hannover Medical School, Berlin, Germany
Hartmut Döhner
Department of Internal Medicine III, University Hospital of Ulm, Albert-Einstein-Allee 23, Germany
Konstanze Döhner
Department of Internal Medicine III, University Hospital of Ulm, Albert-Einstein-Allee 23, Germany
Lars Bullinger
Department of Internal Medicine III, University Hospital of Ulm, Albert-Einstein-Allee 23, Germany;Department of Hematology, Oncology and Tumor Immunology, Charité-University Medicine Berlin, Campus Virchow Klinikum, Berlin, Germany
