Thoracic Cancer (May 2024)

Tracheomediastinal fistula induced by concurrent chemoradiotherapy in small cell lung cancer: A case report and literature review

  • Yoshihiro Yamamoto,
  • Daisuke Shibahara,
  • Taro Mori,
  • Kohei Otsubo,
  • Yoshimasa Shiraishi,
  • Yasuto Yoneshima,
  • Eiji Iwama,
  • Kentaro Tanaka,
  • Yoshinao Oda,
  • Isamu Okamoto

DOI
https://doi.org/10.1111/1759-7714.15270
Journal volume & issue
Vol. 15, no. 13
pp. 1106 – 1111

Abstract

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Abstract Tracheomediastinal fistula is a rare but life‐threatening complication of cancer. We report a case of tracheomediastinal fistula induced by concurrent chemoradiotherapy in limited stage small cell lung cancer. Despite the treatment response, the metastatic paratracheal lymph node increased gradually during concurrent chemoradiotherapy, resulting in the occurrence of tracheomediastinal fistula and mediastinitis. Without any surgical intervention, the patient achieved successful recovery from mediastinitis through antibiotic treatment, although the tracheomediastinal fistula remained open. In this report, we also review previous studies of tracheomediastinal and bronchomediastinal fistulas and summarize the clinical features.

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