Left Atrial Diameter in the Prediction of Thromboembolic Event and Death in Atrial Fibrillation

Abstract

Background: This study aimed to determine the predictive value of left atrial diameter (LAD), and the incremental prognostic value of LAD in combination with CHA2DS2-VASc score for predicting thromboembolic event and all-cause death in patients with non-valvular atrial fibrillation (AF). Methods: This is a prospective study from 27 hospitals during 2014–2017. LADi is LAD data indexed by body surface area, and LADi in the 4th quartile (LADi Q4) was considered high. Results: A total of 2251 patients (mean age 67.4 years, 58.6% male) were enrolled. Mean follow-up duration was 32.3 months. Rates of thromboembolic events and all-cause death were significantly higher in LADi Q4 patients than in LADi Q1–3 patients (2.89 vs. 1.11 per 100 person-years, p p 2DS2-VASc score with the increase in global chi-square for thromboembolism (p = 0.005) and all-cause death (p 2DS2-VASc score in AF patients.

Keywords

• incremental prognostic value
• left atrial size
• thromboembolism
• patients
• non-valvular atrial fibrillation