Nature Communications (Apr 2022)

A synergistic strategy to develop photostable and bright dyes with long Stokes shift for nanoscopy

  • Gangwei Jiang,
  • Tian-Bing Ren,
  • Elisa D’Este,
  • Mengyi Xiong,
  • Bin Xiong,
  • Kai Johnsson,
  • Xiao-Bing Zhang,
  • Lu Wang,
  • Lin Yuan

DOI
https://doi.org/10.1038/s41467-022-29547-3
Journal volume & issue
Vol. 13, no. 1
pp. 1 – 10

Abstract

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Super-resolution microscopy is a powerful tool for cellular studies but requires bright and stable fluorescent probes. Here, the authors report on a strategy to introduce quinoxaline motifs to conventional probes to make them brighter, more photostable, larger Stokes shift, and demonstrate the probes for biosensing applications.