A Point Mutation in the Transcriptional Repressor PerR Results in a Constitutive Oxidative Stress Response in Clostridioides difficile 630Δ
<i>erm</i>

Daniel Troitzsch; Hao Zhang; Silvia Dittmann; Dorothee Düsterhöft; Timon Alexander Möller; Annika-Marisa Michel; Lothar Jänsch; Katharina Riedel; José Manuel Borrero-de Acuña; Dieter Jahn; Susanne Sievers

doi:10.1128/mSphere.00091-21

mSphere (Apr 2021)

A Point Mutation in the Transcriptional Repressor PerR Results in a Constitutive Oxidative Stress Response in Clostridioides difficile 630Δ <i>erm</i>

Daniel Troitzsch,
Hao Zhang,
Silvia Dittmann,
Dorothee Düsterhöft,
Timon Alexander Möller,
Annika-Marisa Michel,
Lothar Jänsch,
Katharina Riedel,
José Manuel Borrero-de Acuña,
Dieter Jahn,
Susanne Sievers

Affiliations

Daniel Troitzsch: Department of Microbial Physiology and Molecular Biology, Institute of Microbiology, University of Greifswald, Greifswald, Germany
Hao Zhang: Institute of Microbiology, Technical University of Braunschweig, Braunschweig, Germany
Silvia Dittmann: Department of Microbial Physiology and Molecular Biology, Institute of Microbiology, University of Greifswald, Greifswald, Germany
Dorothee Düsterhöft: Department of Microbial Physiology and Molecular Biology, Institute of Microbiology, University of Greifswald, Greifswald, Germany
Timon Alexander Möller: Department of Microbial Physiology and Molecular Biology, Institute of Microbiology, University of Greifswald, Greifswald, Germany
Annika-Marisa Michel: Institute of Microbiology, Technical University of Braunschweig, Braunschweig, Germany
Lothar Jänsch: Helmholtz Center for Infection Research, Braunschweig, Germany
Katharina Riedel: Department of Microbial Physiology and Molecular Biology, Institute of Microbiology, University of Greifswald, Greifswald, Germany
José Manuel Borrero-de Acuña: Institute of Microbiology, Technical University of Braunschweig, Braunschweig, Germany
Dieter Jahn: ORCiD; Institute of Microbiology, Technical University of Braunschweig, Braunschweig, Germany
Susanne Sievers: ORCiD; Department of Microbial Physiology and Molecular Biology, Institute of Microbiology, University of Greifswald, Greifswald, Germany

DOI: https://doi.org/10.1128/mSphere.00091-21
Journal volume & issue: Vol. 6, no. 2

Abstract

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The intestinal pathogen Clostridioides difficileC. difficileermC. difficilehttps://doi.org/10.1099/jmm.0.45790-0https://doi.org/10.1016/j.mimet.2007.05.021

Published in mSphere

ISSN: 2379-5042 (Online)
Publisher: American Society for Microbiology
Country of publisher: United States
LCC subjects: Science: Microbiology
Website: https://journals.asm.org/journal/msphere

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