Clinical Case Reports (Dec 2020)

Tocilizumab for treating severe COVID‐19 pneumonia refractory to combined hydroxychloroquine, lopinavir plus ritonavir, and favipiravir: A case series

  • Manoon Surabotsophon,
  • Yingyot Klai‐On,
  • Vipa Thanachartwet,
  • Sirote Khunapornphairote,
  • Supat Chamnanchanunt,
  • Theerapat Racharak,
  • Wannada Laisuan,
  • Duangjai Sahassananda,
  • Samlee Hapunna,
  • Somjit Jinapuk,
  • Suthee Leelasetakul,
  • Varunee Desakorn

DOI
https://doi.org/10.1002/ccr3.3407
Journal volume & issue
Vol. 8, no. 12
pp. 3263 – 3276

Abstract

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Abstract Three patients diagnosed with severe COVID‐19 pneumonia received treatment with hydroxychloroquine combined with lopinavir, ritonavir, and favipiravir. Two patients diagnosed early, received tocilizumab when the pneumonia became severe and survived. The thrid patient was diagnosed late and received tocilizumab when the disease progressed to acute respiratory distress syndrome, and died.

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